منابع مشابه
Origin of Bile Pigments
S. H. ROBINSON (Boston) described a new experimental technique for studying the early labelled component of bilirubin in the ligated bile duct of the Gunn rat. Using 14C bilirubin he measured the total miscible bilirubin pool. In addition, the rate of bile pigment formation following the administration of 2-14C glycine was estimated. This allowed precise assessment of bilirubin and haem product...
متن کاملLv. Studies on Bile Pigments
THE study of bile pigment derivatives is important because these substances represent the end-products of haemoglobin metabolism. The destruction of haemoglobin both normal and pathological can thus be measured by quantitative determination of the urobilin and urobilinogen in urine and faeces. On the other hand, when pathological destruction of haemoglobin can be excluded, urobilinor urobilinog...
متن کاملBile pigments in the stools of infants.
In the normal person bilirubin is converted in the gut into stercobilin. However, unaltered bile pigment occurs in meconium and in the stool of any individual with much intestinal hurry, and has also been shown to be passed at times by some older infants, though this fact does not seem to be widely known. The absence of stercobilin from the stool is usually takenasevidence for total biliary obs...
متن کاملBile Pigments in Pulmonary and Vascular Disease
The bile pigments, biliverdin, and bilirubin, are endogenously derived substances generated during enzymatic heme degradation. These compounds have been shown to act as chemical antioxidants in vitro. Bilirubin formed in tissues circulates in the serum, prior to undergoing hepatic conjugation and biliary excretion. The excess production of bilirubin has been associated with neurotoxicity, in pa...
متن کاملClxi. Transformation of Haemins into Bile Pigments
THAT bile pigment arises in the body by decomposition of haemoglobin is. generally accepted. The work of Fischer and collaborators has confirmed the close chemical relationship between bilirubin and the colour component of haemoglobin. Hitherto nothing was known about the chemical mechanism of this transformation, nor has the formation of a bile pigment from haemoglobin or haemin in vitro been ...
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ژورنال
عنوان ژورنال: Journal of Clinical Pathology
سال: 1953
ISSN: 0021-9746
DOI: 10.1136/jcp.6.2.170-b